This course will focus on the mechanism of action, pharmacological effects and medicinal chemistry of the drugs acting on the CNS which include antianxiety, hypnotics, antipsychotic, antidepressant, antiepileptic, antiparkinsonian, drugs for Alzheimer and migraine as well as general anesthetics, local anesthetics and opioid analgesics. The pathophysiology of diseases involving the central nervous system will also be discussed.